Karyopharm Therapeutics Inc.

  • Medical Science Liaison (MSL) - Southwest

    Job Locations US | US-CA
    Job ID
    # of Openings
    Medical Affairs/HEOR
    Regular Full-Time
  • Overview

    Karyopharm Therapeutics is a clinical-stage pharmaceutical company focused on the discovery and development of novel first in-class drugs directed against nuclear transport targets for the treatment of cancer and other major diseases.


    The Medical Science Liaison (MSL) is responsible for the identification and engagement of a targeted group of national and regional thought leaders/healthcare professionals (HCPs), as well as payers and managed care accounts. This position provides consistent delivery of educational and compliant scientific information in support of Karyopharm’s pipeline.


    • Identify and develop relationships with community/academic thought leaders along with treatment advocates on a local, regional, and national level.
    • Serve as Karyopharm’s scientific representative to the medical community and facilitate the appropriate exchange of scientific information.
    • Provide clinical and economic value information to payers and formulary decision makers.
    • Utilize approved resources to address customer needs, ensuring they are in compliance with all guidelines and regulations.
    • In partnership with clinical operations, support trial awareness, enrollment, and identification of potential sites/investigators for clinical trial participation.
    • Serve as the key liaison for all aspects of investigator sponsored research.
    • Communicate therapeutic market trends which may impact Karyopharm’s pipeline.
    • Participate and support advisory boards and steering committees.
    • Lead and/or participate on committee/project teams which support MSL strategies as delegated by MSL leadership
    • Gain feedback through field interactions with HCPs to uncover collaboration opportunities and pair customer’s unmet needs with available internal resources.
    • The candidate will assume a leadership role by teaching, coaching and mentoring new hires and/or less experienced MSLs and by assuming responsibility for special projects as they arise.


    • Advanced doctoral degree preferred (e.g. PharmD, MD, DO, or PhD). Candidates with a clinical background (e.g. MSN, PA) and extensive hematology/oncology MSL experience will be considered.
    • 1+ years’ MSL experience in oncology strongly preferred; experience in multiple myeloma preferred.
    • Product launch experience a plus.
    • Clinical experience beneficial.
    • Exceptional interpersonal skills.
    • Ability to excel in dynamic settings with short timelines.
    • Strong written/verbal communication and presentation skills.
    • Ability to establish and maintain relationships with influential thought leaders.
    • Thorough understanding of FDA, OIG, HIPAA and other ethical guidelines, laws, and regulations relevant to the pharmaceutical industry.
    • Valid driver’s license and the ability to travel as necessary (up to 75% including some weekends).


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