Karyopharm Therapeutics is a clinical-stage pharmaceutical company, based in Newton, MA, USA, focused on the discovery, development and commercialization of novel, first-in-class agents targeting nuclear transport for the treatment of cancer and other major diseases. Karyopharm is the industry leader in oral Selective Inhibitor of Nuclear Export (SINE) technology, developed to address a central mechanism of oncogenesis via the inhibition of exportins specifically XPO1. Selinexor, Karyopharm’s lead candidate, has been administered to patients with hematologic malignancies or solid tumors in clinical trials worldwide. Karyopharm is currently preparing for its first potential U.S. commercial launch in 2019.
The Finance Manager will assist in the financial management and business partnership support of the Commercial team. The Manager is expected to help teams understand and manage their annual budgets. The Manager will develop both budgets and models associated with Commercial and associated support activities. Additionally, he/she will play a key role in the monthly close process for the Commercial groups. This includes analysis, accrual generation & posting, and reconciliations. He/she will also assist in process and system improvements to enhance visibility into financial performance and increase financial management efficiency. This position reports to the Director of Financial Planning and Analysis, Commercial.
The Finance Manager will work closely with the Commercial functions to accomplish the following: