The Hematology-Oncology Specialist maintains strong professional relationships in the patient care continuum and represents the integrity of Karyopharm Therapeutics by providing approved disease and product information and resources to key decision makers and stakeholders within the oncology community practice setting.   Reporting the Regional Business Director, you will positively impact patients’ when you:   - Develop business plans, market analysis, and strategy that link to strong business results and execute accordingly - Position on-label benefits for appropriate patients to key customer stakeholders to achieve or exceed forecasted sales goals - Resolve issues at account level to ensure access to therapy - Coordinate with colleagues in cross-functional areas including Market Access, Clinical Education, and Medical Affairs to facilitate customer and patient access to Karyopharm product(s) and information - Provide customer feedback to internal stakeholders, sharing best practices, unmet needs, and business opportunities - Assist Marketing function in identifying and inviting appropriate healthcare professionals (HCPs) to promotional and educational events or programs - Develop and maintain mastery of clinical and technical knowledge related to product(s) promoted, the oncology marketplace, and disease management - Foster and develop relationships with Key Opinion Leaders (KOLs), decision makers, influencers, and key stakeholders within the oncology community - Deliver clinical and technical value at medical meetings by staffing promotional booths, as requested - Comply with all laws and regulations and adhere to company compliance guidelines, policy and procedures - Acts with a sense of urgency on behalf of patients and customer

The Data Science Developer will be a key member of the Data Management team and the cross-functional project team on development projects, typically involving large, complex data sets.  This team includes Biostatisticians, Data Scientists, Data Managers, Clinical Project Manager and other organizational stakeholders.  Potential responsibilities include database design, data processing and database loading, and customized data retrieval.  Duties will include participating in company data science and artificial intelligence initiatives.  The ideal candidate is a fast learner, a problem solver, a good communicator, and self-motivated forward thinker.   Reporting to our Head of Data Management, you will positively impact patients’ when you: - Understand clinical trial data, genomic data, and real-world evidence (RWE) data. - Design and utilize an integrated data structure that links multiple data sources that allows for data mining, machine learning, and artificial intelligence. - Oversee, build, and maintain data pipelines to automate data processing tasks. - Support the import and export of data to support the use of an integrated data environment. - Develop and support the User Interface (UI). - Administer and maintain user access to data analytics.

Accountable for the oversight and deliverables of all ex-US and ex-Canada Clinical Trial Applications (CTA) for Karyopharm’s development programs. This candidate will be an active member of the respective Study Teams and will ensure cross-functional alignment and on-time / right-first-time submission and approval of CTA filings.   Reporting to our SVP, Regulatory Affairs, you will positively impact patients’ when you:   - Plan, execute and oversee all ex-US/ex-Canada CTA submissions in alignment with the respective program strategies and study team timelines - Work hand-in-hand with internal Regulatory team to ensure execution excellence of all CTAs - Oversee and manage all CRO contributions to Karyopharm’s CTAs and escalate critical issues as needed - Ensure work orders and contracts of CROs are current to support all of Karyopharm’s CTA deliverables - Develop regulatory strategies and author drafts of various documents intended for submission to global health authorities and Ethics Committees pertaining to CTAs - Lead internal and external stakeholders to respond to Competent Authority information requests pertaining to the CTAs in an expeditious and high quality manner - Be the internal expert of the EU Clinical Trial Directive/Regulation including regulatory submission requirements, as well as IVDR clinical submissions - Assess change controls that pertain to CTAs and define regulatory requirements and perform risk assessments, as needed - Act as the contact for ex-US/ex-Canada regulatory agencies relevant to assigned CTAs, where applicable - Prepare and deliver effective presentations for external and internal stakeholders on all relevant CTA activities

If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared mission. Creating and delivering medicine for cancer can only be done through focus, dedication, and heart. We hire exceptional people and trust each other to work in whatever way lets us, be us – whether that’s onsite, from home, or anywhere in between.    Oursummer intern program, which will run from May 27th– Aug 8th, allows students to gain real world work experience in a high energy, collaborative work culture.    This intern will assist in QMS processes and systems administration to ensure consistent daily operations enabling GxP compliance and inspection-readiness. QMS administration processes include: Document Control, Deviations Management, Investigations Management, CAPA Management, Validation, Change Control, Risk Management, Training Management, Vendor Qualification, and GxP Auditing. Under supervision of functional leads, intern will assist with day-to-day process/system administration and actively participate in QMS administration process improvement projects as assigned. Will interact with 5 functional leads and end users throughout the organization.   This internship will support continuous product supply for Karyopharm’s drug products (IMP) utilized in clinical trials.  The individual will work with the teams managing internal and external tasks and customers in order to accomplish project objectives and to understand the needs of the clinical trials. The Clinical Supply Chain Intern will support Clinical Supply Chain initiatives and continuous improvement activities.   Responsibilities - Participate in cross-functional Project Team Meetings - Partner with PM to review and understand the Clinical Supply study process - Shadow the PM who coordinate and monitor label development process and packaging timelines with the vendors - Learn how to process Temperature Excursions associated to study shipments through approval - Organize and file various trial related documents - Generate Quarterly Reports and the KPTI Performance and Risk Indicators. - Oversight/participation of Clinical Trials processes

The Hematology-Oncology Specialist maintains strong professional relationships in the patient care continuum and represents the integrity of Karyopharm Therapeutics by providing approved disease and product information and resources to key decision makers and stakeholders within the oncology community practice setting.   Reporting the Regional Business Director, you will positively impact patients’ when you:   - Develop business plans, market analysis, and strategy that link to strong business results and execute accordingly - Position on-label benefits for appropriate patients to key customer stakeholders to achieve or exceed forecasted sales goals - Resolve issues at account level to ensure access to therapy - Coordinate with colleagues in cross-functional areas including Market Access, Clinical Education, and Medical Affairs to facilitate customer and patient access to Karyopharm product(s) and information - Provide customer feedback to internal stakeholders, sharing best practices, unmet needs, and business opportunities - Assist Marketing function in identifying and inviting appropriate healthcare professionals (HCPs) to promotional and educational events or programs - Develop and maintain mastery of clinical and technical knowledge related to product(s) promoted, the oncology marketplace, and disease management - Foster and develop relationships with Key Opinion Leaders (KOLs), decision makers, influencers, and key stakeholders within the oncology community - Deliver clinical and technical value at medical meetings by staffing promotional booths, as requested - Comply with all laws and regulations and adhere to company compliance guidelines, policy and procedures - Acts with a sense of urgency on behalf of patients and customer

The Hematology-Oncology Specialist maintains strong professional relationships in the patient care continuum and represents the integrity of Karyopharm Therapeutics by providing approved disease and product information and resources to key decision makers and stakeholders within the oncology community practice setting.   Reporting the Regional Business Director, you will positively impact patients’ when you:   - Develop business plans, market analysis, and strategy that link to strong business results and execute accordingly - Position on-label benefits for appropriate patients to key customer stakeholders to achieve or exceed forecasted sales goals - Resolve issues at account level to ensure access to therapy - Coordinate with colleagues in cross-functional areas including Market Access, Clinical Education, and Medical Affairs to facilitate customer and patient access to Karyopharm product(s) and information - Provide customer feedback to internal stakeholders, sharing best practices, unmet needs, and business opportunities - Assist Marketing function in identifying and inviting appropriate healthcare professionals (HCPs) to promotional and educational events or programs - Develop and maintain mastery of clinical and technical knowledge related to product(s) promoted, the oncology marketplace, and disease management - Foster and develop relationships with Key Opinion Leaders (KOLs), decision makers, influencers, and key stakeholders within the oncology community - Deliver clinical and technical value at medical meetings by staffing promotional booths, as requested - Comply with all laws and regulations and adhere to company compliance guidelines, policy and procedures - Acts with a sense of urgency on behalf of patients and customer