Karyopharm Therapeutics Inc.

AD / Director Program Management

Job Locations US-Remote
Job ID
2025-2380
# of Openings
1
Category
Research and Development
Type
Regular Full-Time

Role Overview & Key Functions:

As a Karyopharmer, reporting to the Senior Director Program Management, you will positively impact patients’ when you:

 

  • Acts as the COO of Program, partnering with the Program Lead to drive team alignment on program strategy and operationalize the strategic vision
  • Provides an independent voice to shape the program strategy and acts as an integrator of cross-functional input to drive optimal decisions for the program
  • Leads effective Program Team meetings and presents program strategy to various audiences
  • Accountable for the cross-functional execution of one or more program strategy plans. Can be assigned to any disease area, at any stage of development
  • Manages program timeline, cost, quality, and risk mitigation as well as timely escalation where needed
  • Acts as a leader in the PM organization to help build cross-portfolio capabilities. Recognizes consistent challenges and innovates solutions, shares best practices and coaches more junior PMs

Candidate Profile & Requirements:

  • Manages the effective operations of Karyopharm’s cross-functional program teams, focused on the development of one or more disease area programs
  • Partners with the Program Lead to drive development of the Program Strategy Plan, adding value by deriving insights from cross-functional discussions and summarizing those insights in a plan that can be easily communicated and implemented across the enterprise
  • Partners with the Program Lead to coordinate the development, and implementation of high quality, global, cross-functional, integrated project plans that are aligned with the program strategy
  • Fosters a high-performing team by championing team norms, operating principles and introducing best practices. Monitors the heath and operating efficiency of the team on a regular basis and shares feedback
  • Mentors and coaches team members to drive accountability, alignment, and excellence
  • Facilitates effective business decisions by ensuring integration of key cross-functional input and robust analysis of scenarios. Ensures all decisions are assessed as to their impacts and communicated to stakeholders in a transparent and timely manner
  • Highlights key interdependencies and downstream impacts of strategic decisions to stakeholders
  • For programs that are being jointly developed, works closely with alliance management and partner counterparts to ensure appropriate level of engagement in program strategy discussions   
  • Responsible for maintaining and updating program dashboards for assigned program team(s), provides regular status reports on key deliverables, risks and issues to Program Lead
  • Proactively coordinates risk management and ensures contingency and/or risk mitigation plans are developed
  • Works with functions to procure adequate resources to achieve project objectives in planned timeframes
  • Acts as a change agent and leads process improvement initiatives for continuous improvement and as it relates to improving project delivery
  • May delegate project level tasks/follow-up and provides oversight to Project Manager(s) with potential for direct reporting responsibility
  • Works creatively and analytically in a problem-solving environment demonstrating teamwork, innovation, and excellence

 

QUALIFICATIONS:

  • Bachelors degree in a science related or business related field required. Advanced degree preferred (e.g., MBA, MS, PhD, PharmD).
  • Five (5) or more years of demonstrated drug development project/program management experience with 7+ years of relevant experience in the Pharmaceutical or related Life Sciences industry.
  • Strong knowledge in drug discovery and development and/ or clinical research or related health sciences field with solid understanding of project strategy, interdependencies, and disease content to contribute to strategic discussions
  • Experience with operational study start-up into Registrational/Phase 3 trials with a deep understanding of the necessary steps required for market application submissions in multiple regions (US, EU, Japan, China)
  • Well-developed program leadership and strategic thinking skills, experience in development of Program Strategy Plans
  • Experience in partnering with functional leads across the organization to meet strategic goals and demonstrated ability to collaborate in a cross-functional environment
  • Excellent organizational skills ability to manage several priorities simultaneously
  • Ability to influence without authority and to act as a leader on a wide range of complex activities where judgment and expertise are critical to project success
  • Strong communicator able to integrate information and tailor messages to audience, including senior leaders
  • Ability to manage difficult discussions with stakeholders and capitalize on conflict
  • Ability to lead the team in an efficient process for critical path analyses and scenario planning

 

 

At Karyopharm, base pay is one part of a competitive total rewards package that includes comprehensive benefits (medical, dental, vision, 401(k), and more), equity and the potential to receive annual target bonuses. Actual pay is based on factors such as location, experience, skills, education, and internal equity. We maintain broad salary ranges to reflect market conditions and the specialized nature of our work. The anticipated base salary range for this position is $205 K - $275 K USD.

Our Value Proposition:

At Karyopharm, we live and demonstrate our ICARE values every day!

 

Karyopharm Therapeutics is a global commercial-stage pharmaceutical company focused on the discovery and development of novel first in-class drugs directed against nuclear transport targets for the treatment of cancer and other major diseases.

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