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Karyopharm Therapeutics Inc. (the "Company") is an equal opportunity employer. All qualified applicants will be considered without regard to age, race, color, sex, religion/creed, national origin, marital status, ancestry, citizenship, military, reservist or veteran status, pregnancy, sexual orientation or preference, gender identity, gender expression, physical or mental disability, genetic predisposition or carrier status, or any other category protected under applicable federal, state or local law. Consistent with its obligations under applicable law, the Company will make reasonable accommodations for qualified individuals with disabilities. If you require an accommodation in the application process, please contact a member of the Company’s Human Resources department.
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The Associate Director, Document Management and Trial Master File (TMF) provides strategic and operational leadership for the management of GxP Documents in the Trial Master Files (TMF/eTMF) across Karyopharm clinical programs. This role is responsible for ensuring TMFs are complete, accurate, and inspection-ready, while leading TMF staff, overseeing vendors, driving process improvement, and partnering cross-functionally to support successful study execution. The Associate Director serves as a subject matter expert for TMF processes and contributes to the continuous evolution of TMF strategy, quality, and compliance.
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared mission
The Sr Director, Clinical Research Scientist position serves a key role within the Clinical Development R&D team. The Sr Director, CRS works closely with the assigned study team(s) and medical director(s) to support the activities associated with one or more clinical studies. This position collaborates with clinical team members as well as with functions outside of clinical to provide high quality and timely deliverables.
As a Karyopharm, reporting to the Executive Director US Medical Affairs Strategy, you will positively impact
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared...
This internship offers a high-impact opportunity to work across multiple functions at Karyopharm, with exposure to Strategy & Portfolio Management, Business Operations, and Program Management. The intern will play a key role in evaluating and enhancing Program Team resources that define the drug development end-to-end process, ensuring they are accurate, up to date,...
As a Karyopharm, reporting to the Executive Director, GMP (Good Manufacturing Practice) Quality, you will positively impact patients’ lives by:
Karyopharm Therapeutics is a commercial-stage oncology company focused on developing novel therapies for patients with cancer, particularly in areas where treatment options have remained limited for far too long. Our team is driven by curiosity, urgency, and the belief that meaningful innovation can reshape patients’ lives.
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared...
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared...
This role will support continuous product supply for Karyopharm’ s drug products (IMP) utilized in clinical trials. The individual will work with teams managing...
If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That’s why we’ve built an environment centered around support, flexibility, and a shared mission....
We are looking for an experienced professional who understands and can live our corporate ICARE values of Innovation, Courage, Alignment/Accountibility, Resilience, and Energy every day as we drive to bring new therapeutics to the market in the fight against cancer. The Regional Business Director provides leadership and direction of field sales representatives to achieve Karyopharm objectives, meet customer needs, foster team development and drive sales of XPOVIO within approved indications.
Reporting to our...
As a Karyopharmer, reporting to the Senior Director Program Management, you will positively impact patients’ when you:
- Acts as the COO of Program, partnering with the Program Lead to drive team alignment on program strategy and operationalize the strategic vision
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We are looking for a personable, practical legal advisor with an understanding of the False Claims Act; Food, Drug & Cosmetic Act; Anti-Kickback Statute; and other healthcare laws and regulations. You will have high visibility throughout the organization, supporting core business activities and providing counsel to cross-functional teams. You will be empowered to develop strong and positive working relationships with colleagues at all levels. Experience in pharmaceutical / life sciences advising, ability to work in a fast-paced environment, and willingness to be a flexible, business-oriented team player are required. The Brand Counsel role reports to the...
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Not ready to apply? Not seeing a job that matches your interests? Join our Talent Community to stay connected, By signing up, you’ll gain access to updates about career opportunities, company news, and information tailored to your professional interests. Whether you are exploring future roles or simply would like to stay informed, our Talent Community keeps you updated and inspired.
We're always eager to connect with driven professionals who are ready to make an impact. Whether your...